Latisse (bimatoprost ophthalmic solution 0.03%) is a prescription medication that promotes eyelash growth, improving their length, thickness, and darkness. It’s approved by the Food and Drug Administration (FDA) specifically for eyelash hypotrichosis (inadequate lashes).
Despite its current use, you might be surprised that bimatoprost, Latisse’s active ingredient, was first used to treat glaucoma (as LUMIGAN); the eyelash-growth use came later.
In this article, we’ll discuss how Latisse works, how to use it carefully, and how it can affect your eyes if you’re not careful.
How Does Latisse Work?
Latisse belongs to a class of medications known as prostaglandin analogs. It was initially developed to treat elevated intraocular pressure (eye pressure).
However, doctors discovered that this medication significantly extends eyelashes' anagen (growth) phase, allowing them to grow longer and thicker before naturally shedding.
How Effective Is Latisse?
In clinical trials, regular nightly application resulted in eyelashes that were, on average, 25% longer and 106% thicker after 16 weeks. However, it's essential to maintain realistic expectations.
Noticeable results typically become visible around 8 weeks and fully develop by 16 weeks. However, the improvements aren’t permanent.
If you stop using Latisse, your lashes gradually revert to their original length and fullness. Here’s a general timeline of the results most people see with consistent use:
- 4 weeks. Increased eyelash length
- 8 weeks. Thicker, darker lashes
- 12 weeks. Enhanced results compared to previous weeks
- 16 weeks. Dramatically thicker, darker, and longer lashes
What Happens When You Stop Using Latisse?
Continue the treatment until you complete the full 16-week course even if you’re satisfied earlier. If you stop using Latisse, your eyelashes will gradually return to their previous appearance.
After 16 weeks, your lashes should be noticeably fuller. At this point, talk to your doctor about ongoing Latisse treatment. The FDA label recommends once-nightly application; any reduced-frequency “maintenance” use is off-label and should be guided by your clinician.
What are the Side Effects of Latisse?
Like any medication, Latisse can cause side effects. However, most side effects are mild and reversible, occurring in 3 to 4% of users.
The most common side effects include:
- Itchy, red eyes
- Mild irritation
- Temporary darkening of the eyelid skin
- Periorbitopathy (changes to the fat around your eyes)
One rare side effect is the darkening of your iris (iris pigmentation). This is likely permanent.
Also, be aware that if you wear contact lenses, Latisse can discolor them. Always remove your lenses before applying the solution and wait 15 minutes before putting them back in.
Who Should Avoid Using Latisse?
Latisse isn't suitable for everyone. You should avoid or carefully consider using Latisse if you:
- Have active eye infections or inflammation (e.g., uveitis)
- Are using intraocular pressure-lowering medications for glaucoma (due to possible interactions)
- Have macular edema
- Are aphakic, or are pseudophakic with a torn posterior lens capsule, or have other risk factors for macular edema
- Are pregnant or breastfeeding (consult your doctor first, as safety data is limited)
How to Prevent Problems
If you want to use Latisse safely and reduce the risk of irritation or infection, consider the following:
- Use one sterile applicator per eye every night and never reuse applicators.
- Do not apply Latisse to your lower eyelid.
- Remove contact lenses before applying, and wait at least 15 minutes before reinserting them.
- Avoid excess drops, as using more doesn't enhance results.
If you develop a new eye condition or infection, seek prompt medical advice about whether to continue; you may be advised to pause use.
You should also contact your doctor if you experience an allergic reaction to Latisse, an infection, or decreased vision.
How Much Does Latisse Cost?
Because Latisse is prescription-only, you must first consult a medical professional, either in person at a doctor's office or via telehealth consultation.
In the U.S. in 2025, a brand-name 5 mL bottle typically costs about $170 to $235, while discounted generics can be around $55 to $70 depending on pharmacy and coupons. As insurers consider Latisse cosmetic, it's rarely covered by standard health insurance.
Alternative Options to Latisse
You can try alternative products or home remedies if you’re looking for fuller lashes but don’t want to use Latisse.
Cosmetic aisles are stocked with over-the-counter (OTC) eyelash serums that promise similar effects to Latisse. However, isopropyl cloprostenate, the prostaglandin analog often found in these items, is not FDA-approved. The safety and efficacy of OTC products are largely unknown.
Various natural remedies that reputedly encourage and enhance eyelash growth include:
- Castor oil
- Aloe Vera
- Vitamin E
- Green tea
- Olive oil
You can apply these treatments to your lashes using a clean mascara brush or cotton swab. Then, leave overnight and rinse in the morning. While these treatments are popular, little scientific evidence supports claims of lash growth.
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