Corneal Edema Symptoms, Causes & Treatments

8 sources cited
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What is Corneal Edema?

Corneal edema is a condition that is characterized by the swelling of the eye’s cornea. The cornea is the clear tissue layer of the eye that transmits and focuses light so that you can see.

It’s made up of five important layers:

  1. Epithelium
  2. Bowman’s Membrane
  3. Stroma
  4. Descemet’s Membrane
  5. Endothelium
Three Main Layers of the Eye picture

Each layer works in unison to capture light, which ultimately enhances your vision. The cornea, therefore, is an integral part of your eye. Damage to the cornea can significantly impair your vision and affect the proper functioning of your eye. 

Corneal edema usually occurs in people who are 50 years old or older. But anyone at any age can develop this eye condition.

What Causes Corneal Edema?

There are a few common causes of corneal edema:

  • Keratitis (inflamed cornea due to medical conditions like herpes simplex viral infections)
  • Certain medications
  • Wearing irritating contact lenses too often
  • Glaucoma
  • Eye surgery

Most commonly, it happens when there’s a buildup of fluid in your eye.

The endothelium of the cornea controls the build-up and release of fluid.

You can damage the endothelium of your cornea and develop corneal edema a few ways:

  • Fuchs’ endothelial dystrophy (a disease that affects the endothelial cells)
  • Endotheliitis (an immune response to herpes)
  • Other endothelial dystrophies
  • Other eye diseases
  • Ocular trauma
  • Infections
  • Corneal transplant problems 
  • Eye surgery
  • Over-wearing contact lenses

What are the Symptoms of Corneal Edema?

Corneal edema can be uncomfortable due to swelling of the cornea and any endothelial damage.

You may experience some or all of these symptoms if you have corneal edema:

  • Eye pain
  • Glare
  • Blurriness
  • Distorted eyesight
  • Seeing halos or rings around light
  • Increased sensitivity to light
  • Eye soreness
  • Scratching sensation in the eye
  • Blisters on the cornea (in severe cases)

Diagnosis of Corneal Edema

Your ophthalmologist will discuss your symptoms and medical history. Then they will conduct an eye exam to look at your cornea.

They’ll look out for any clouding of your cornea by using magnifying tools such as slit lamps and ophthalmoscopes.

They may also do an ultrasound on your eye or measure your cornea’s thickness via a process that is known as pachymetry.

If you are diagnosed with corneal edema, your ophthalmologist will share and discuss some treatment options for you.

Corneal Edema Treatment 

Fortunately, there are both surgical and non-surgical options to treat corneal edema.

Depending on your diagnosis, some surgical treatment options may include the following:

  • Corneal transplant
  • Lens implant exchanges (a dislocated lens implant may cause corneal edema)
  • Removal of vitreous materials or remaining lens materials after cataract surgery
  • Descemet Stripping Endothelial Keratoplasty (DSEK) to replace the corneal endothelium through a small incision

If your case isn’t so severe, non-surgical treatment options may include the following:

  • Switching to a new type of contact lenses
  • Switching to glasses instead of contact lenses
  • Taking antiviral drugs (for herpes infections), beta-adrenergic blockers (or other glaucoma medications), or corticosteroids (to reduce inflammation)
  • Using ointments
  • Taking diuretics
  • Using hypertonic saline drops
  • Using prescription eye drops
  • Using a bandage contact lens
  • Practicing general eye care

Corneal Edema FAQs

Here are answers to some of the most frequently asked questions about corneal edema.

Does corneal edema cause headaches?

Corneal edema can cause headaches for some people.

Because of the swelling and your impaired vision, you may find yourself straining your eyes more often so that you can see more clearly.

Increased sensitivity to light and foreign particles may also induce headaches. However, not everyone who develops corneal edema experiences headaches.

Will corneal edema go away?

Corneal edema may go away on its own if it isn’t too serious. If it doesn’t clear up over time, however, corneal edema can still go away with the proper treatment.

There are both surgical and non-surgical options to treat corneal edema. It’s important to talk to your ophthalmologist about the best treatment option for you given your diagnosis, budget, lifestyle, and other factors that could influence your decision.

Is corneal edema serious?

Corneal edema is not always serious.

In fact, it’s common in postoperative patients who’ve undergone eye surgeries and often happens in people 50 years of age and older.

Depending on the severity of your corneal edema diagnosis, it can have significant effects on your visual acuity if left untreated.

8 Cited Research Articles
  1. “Corneal Edema.” Corneal Edema | Columbia Ophthalmology, www.columbiaeye.org/education/digital-reference-of-ophthalmology/lens-cataract/surgery-complications-0/corneal-edema
  2. “Corneal Edema.” Drs. Campbell, Cunningham, Taylor, and Haun, 15 July 2020, www.ccteyes.com/corneal-edema/
  3. “Corneal Edema: Causes, Symptoms, Treatment: Dean McGee.” DMEI, 28 May 2020, dmei.org/services-specialties/cornea-external-diseases/corneal-edema/.
  4. “Corneal Swelling.” MedStar Georgetown University Hospital, www.medstargeorgetown.org/our-services/ophthalmology/conditions/corneal-swelling/
  5. MD, Omar R Chaudhary. “What Is the Treatment for Corneal Edema?” American Academy of Ophthalmology, 16 Feb. 2018, www.aao.org/eye-health/ask-ophthalmologist-q/corneal-edema-treatment
  6. “Ophthalmologist Richmond VA: Glen Allen VA.” Richmond Eye Associates PC RSS, www.richmondeye.com/eyehealth_blur
  7. “Our Products.” Bausch Lomb. See Better. Live Better., www.bausch.com/our-products/dry-eye-products/corneal-edema
  8. “What Are the Causes of Corneal Edema?” Fort Lauderdale Eye Institute, 13 Apr. 2020, flei.com/what-are-the-causes-of-corneal-edema/.
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